KMID : 1031220120160020059
|
|
Journal of Korean Epilepsy Society 2012 Volume.16 No. 2 p.59 ~ p.62
|
|
Anti-GABA-B Receptor Autoimmune Encephalitis
|
|
Park Byeong-Su
Kim Young-Soo Lee Soon-Tae Jung Keun-Hwa Lee Sang-Kun Chu Kon
|
|
Abstract
|
|
|
Autoimmune encephalitis is a group of disorders that predominantly affects the limbic system, with or without an associated neoplasm. Recently GABAB receptor antibody has been identified in a subset of encephalitides. We report a case of anti-GABAB receptor antibody encephalitis in a 64-year-old woman, who presented with transient, recurrent abnormal behavior and complex partial seizures. She had a history of breast cancer, which was in complete remission and her workup, including blood, imaging and routine cerebrospinal fluid studies was unremarkable. Indirect immunofluorescence assays with patient¡¯s serum revealed the presence of autoantibodies against GABAB receptor. She showed significant improvement after initiating immunotherapy. This case illustrates the importance of autoantibody testing in the diagnosis of encephalitis.
|
|
KEYWORD
|
|
Immune-mediated encephalitis, Autoimmune encephalitis, Limbic encephalitis
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|